Anti-LARP6 antibody (1-320) (STJ118758)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal LARP6 (1-320) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | LARP6 |
| Gene ID | 55323 |
| Uniprot ID | LARP6_HUMAN |
| Immunogen Region | 1-320 |
| Immunogen Sequence | MAQSGGEARPGPKTAVQIRV AIQEAEDVDELEDEEEGAET RGAGDPARYLSPGWGSASEE EPSRGHSGTTASGGENERED LEQEWKPPDEELIKKLVDQI EFYFSDENLEKDAFLLKHVR RNKLGYVSVKLLTSFKKVKH LTRDWRTTAHALKYSVVLEL NEDHRKVRRTTPVPLFPNEN LPSKMLLVYDLYLSPKLWAL ATPQKNGRVQEKVMEHLLKL FGTFGVISSVRILKPGREL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human LARP6 (NP_060827.2). |
Additional Info
| Tissue Specificity | Expressed in numerous tissues. |
| Function | Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9. |
| Protein Name | La-Related Protein 6AcheronAchnLa Ribonucleoprotein Domain Family Member 6 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusShuttles Between The Nucleus And The Cytoplasm |
| Alternative Antibody Names | Anti-La-Related Protein 6 antibodyAnti-Acheron antibodyAnti-Achn antibodyAnti-La Ribonucleoprotein Domain Family Member 6 antibodyAnti-LARP6 antibody |
Information sourced from Uniprot.org