• Immunohistochemical analysis of paraffin-embedded human-lung-cancer, antibody was diluted at 1:200
  • Immunohistochemical analysis of paraffin-embedded human-lung-cancer, antibody was diluted at 1:200
  • Western blot analysis of mouse-lung mouse-heart 293T Hela 3T3 lysate, antibody was diluted at 500. Secondary antibody was diluted at 1:20000

Anti-LAMP3 antibody (261-310 aa) (STJ98762)

SKU:
STJ98762

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Lysosome-associated membrane glycoprotein 3 (261-310 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:500-200
ELISA 1:10000-20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: LAMP3
Gene ID: 27074
Uniprot ID: LAMP3_HUMAN
Immunogen Region: 261-310 aa
Specificity: The antibody detects endogenous DC-LAMP
Immunogen: Synthetic peptide from the human protein at the amino acid range 261-310
Function Lysosomal membrane glycoprotein which plays a role in the unfolded protein response (UPR) that contributes to protein degradation and cell survival during proteasomal dysfunction. Plays a role in the process of fusion of the lysosome with the autophagosome, thereby modulating the autophagic process. Promotes hepatocellular lipogenesis through activation of the PI3K/Akt pathway. May also play a role in dendritic cell function and in adaptive immunity. (Microbial infection) Plays a positive role in post-entry steps of influenza A virus replication, either virus uncoating, cytosolic transport, or nuclear import of viral components, and promotes nuclear accumulation of influenza nucleoprotein/NP at early stages of viral infection. (Microbial infection) Supports the FURIN-mediated cleavage of mumps virus fusion protein F by interacting with both FURIN and the unprocessed form but not the processed form of the viral protein F. (Microbial infection) Promotes the intracellular proliferation of Salmonella typhimuium.
Protein Name Lysosome-Associated Membrane Glycoprotein 3
Lamp-3
Lysosomal-Associated Membrane Protein 3
Dc-Lysosome-Associated Membrane Glycoprotein
Dc Lamp
Protein Tsc403
Cd Antigen Cd208
Cellular Localisation Cell Surface
Lysosome Membrane
Single-Pass Type I Membrane Protein
Cytoplasmic Vesicle Membrane
Early Endosome Membrane
During Dendritic Cell Maturation
Detected On Cytoplasmic Vesicles (The Mhc Ii Compartment) That Contain Mhc Ii Proteins
Lamp1
Lamp2 And Lamp3
Detected On Lysosomes In Mature Dendritic Cells
Alternative Antibody Names Anti-Lysosome-Associated Membrane Glycoprotein 3 antibody
Anti-Lamp-3 antibody
Anti-Lysosomal-Associated Membrane Protein 3 antibody
Anti-Dc-Lysosome-Associated Membrane Glycoprotein antibody
Anti-Dc Lamp antibody
Anti-Protein Tsc403 antibody
Anti-Cd Antigen Cd208 antibody
Anti-LAMP3 antibody
Anti-DCLAMP antibody
Anti-TSC403 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance