| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Laminin subunit gamma-2 (1021-1070 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 IHC-P 1:100-1:300 ELISA 1:20000 IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | LAMC2 |
| Gene ID: | 3918 |
| Uniprot ID: | LAMC2_HUMAN |
| Immunogen Region: | 1021-1070 aa |
| Specificity: | Laminin Gamma-2 Polyclonal Antibody detects endogenous levels of Laminin Gamma-2 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the C-terminal region of human LAMC2 at the amino acid range 1021-1070 |
| Post Translational Modifications | O-glycosylated.contains chondroitin sulfate (CS). CS attachment is on either Ser-803 or Ser-805. |
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Ladsin exerts cell-scattering activity toward a wide variety of cells, including epithelial, endothelial, and fibroblastic cells. |
| Protein Name | Laminin Subunit Gamma-2 Cell-Scattering Factor 140 Kda Subunit Csf 140 Kda Subunit Epiligrin Subunit Gamma Kalinin Subunit Gamma Kalinin/Nicein/Epiligrin 100 Kda Subunit Ladsin 140 Kda Subunit Laminin B2t Chain Laminin-5 Subunit Gamma Large Adhesive Scatter Factor 140 Kda Subunit Nicein Subunit Gamma |
| Database Links | Reactome: R-HSA-1474228 Reactome: R-HSA-2022090 Reactome: R-HSA-2214320 Reactome: R-HSA-3000157 Reactome: R-HSA-3000171 Reactome: R-HSA-446107 Reactome: R-HSA-8874081 |
| Cellular Localisation | Secreted Extracellular Space Extracellular Matrix Basement Membrane Major Component |
| Alternative Antibody Names | Anti-Laminin Subunit Gamma-2 antibody Anti-Cell-Scattering Factor 140 Kda Subunit antibody Anti-Csf 140 Kda Subunit antibody Anti-Epiligrin Subunit Gamma antibody Anti-Kalinin Subunit Gamma antibody Anti-Kalinin/Nicein/Epiligrin 100 Kda Subunit antibody Anti-Ladsin 140 Kda Subunit antibody Anti-Laminin B2t Chain antibody Anti-Laminin-5 Subunit Gamma antibody Anti-Large Adhesive Scatter Factor 140 Kda Subunit antibody Anti-Nicein Subunit Gamma antibody Anti-LAMC2 antibody Anti-LAMB2T antibody Anti-LAMNB2 antibody |
Information sourced from Uniprot.org