Lambda Light chain antibody western blot human plasma STJA0035471

Anti-Lambda Light chain antibody [R51-1S-3] (STJA0035471)

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STJA0035471
£133.50 - £281.50
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Short Description :Rabbit monoclonal anti-Lambda Light chain for use in WB, IHC-P, ICC, IF and FC in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC-P/ICC/IF/FC
Host:Rabbit
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :R51-1S-3
Isotype:IgG
Conjugation:Unconjugated
Purification:Affinity Chromatography
Dilution Range:WB 1:500-1:1000
IHC 1:100-1:200
IF 1:50-1:200
FC 1:50
Formulation:Liquid in PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:IGLV1-51Uniprot ID=LV151_HUMAN"
Immunogen:A synthesized peptide derived from human Lambda Light chain
Function V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.
Protein Name Immunoglobulin Lambda Variable 1-51
Ig Lambda Chain V-I Region Bl2
Ig Lambda Chain V-I Region Eps
Ig Lambda Chain V-I Region New
Ig Lambda Chain V-I Region Nig-64
Cellular Localisation Secreted
Cell Membrane
Alternative Antibody Names Anti-Immunoglobulin Lambda Variable 1-51 antibody
Anti-Ig Lambda Chain V-I Region Bl2 antibody
Anti-Ig Lambda Chain V-I Region Eps antibody
Anti-Ig Lambda Chain V-I Region New antibody
Anti-Ig Lambda Chain V-I Region Nig-64 antibody
Anti-IGLV1-51 antibody

Information sourced from Uniprot.org

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