Anti-Lambda antibody [Lamb14] (STJ16100382)

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STJ16100382
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Short Description :Mouse monoclonal anti-Lambda for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC-P
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :Lamb14
Isotype:IgG2a
Conjugation:Unconjugated
Dilution Range:IHC 1:100 – 1:500
Formulation:Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Storage Instruction:Store at 2-8°C for up to 1-year, upon receipt.
Background The antibody detects surface immunoglobulin on normal and neoplastic B-cells. Anti-lambda staining is seen in B-cell follicles of human lymphoid tissue. When dealing with B-cell neoplasms, the determination of light chain ratios remains helpful. Most B-cell lymphomas express either kappa or lambda light chains, whereas reactive proliferations display a mixture of kappa and lambda positive cells. If only a single light chain type is detected, a lymphoproliferative disorder is very likely.

Information sourced from Uniprot.org