| Short Description : | Mouse monoclonal anti-Lambda for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC-p |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | IHC709 |
| Isotype: | IgG1 |
| Conjugation: | Unconjugated |
| Formulation: | Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide |
| Storage Instruction: | Store at 2-8°C for up to 1 year. Do not freeze. |
| Specificity: | Tested and validated on tonsil tissue. |
| Background | Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five types) and two light chains-kappa and lambda. The determination of light chain ratio is critical in evaluating B-cell neoplasms, as the majority of B-cell lymphomas express either kappa or lambda light chains, while a mixture of kappa and lambda is characteristic of reactive proliferations. Antibodies against lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin s lymphomas. |
Information sourced from Uniprot.org
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