• Western blot analysis of lysates from Rat liver, using LACTB Rabbit polyclonal antibody (STJ11105406) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-LACTB antibody (116-255) (STJ11105406)

SKU:
STJ11105406

£112.50 - £522.50
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Serine Beta-Lactamase-Like Protein Lactb-Mitochondrial (116-255) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: LACTB
Gene ID: 114294
Uniprot ID: LACTB_HUMAN
Immunogen Region: 116-255
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 116-255 of human LACTB (NP_116246.2).
Immunogen Sequence: HRIKDEVGAPGIVVGVSVDG KEVWSEGLGYADVENRVPCK PETVMRIASISKSLTMVALA KLWEAGKLDLDIPVQHYVPE FPEKEYEGEKVSVTTRLLIS HLSGIRHYEKDIKKVKEEKA YKALKMMKENVAFEQEKEGK
Tissue Specificity Expressed predominantly in skeletal muscle.
Function Mitochondrial serine protease that acts as a regulator of mitochondrial lipid metabolism. Acts by decreasing protein levels of PISD, a mitochondrial enzyme that converts phosphatidylserine (PtdSer) to phosphatidylethanolamine (PtdEtn), thereby affecting mitochondrial lipid metabolism. It is unclear whether it acts directly by mediating proteolysis of PISD or by mediating proteolysis of another lipid metabolism protein. Acts as a tumor suppressor that has the ability to inhibit proliferation of multiple types of breast cancer cells: probably by promoting decreased levels of PISD, thereby affecting mitochondrial lipid metabolism.
Protein Name Serine Beta-Lactamase-Like Protein Lactb - Mitochondrial
Cellular Localisation Mitochondrion
Alternative Antibody Names Anti-Serine Beta-Lactamase-Like Protein Lactb - Mitochondrial antibody
Anti-LACTB antibody
Anti-MRPL56 antibody
Anti-UNQ843 antibody
Anti-PRO1781 antibody

Information sourced from Uniprot.org

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