Anti-KRT16 antibody (400-473 aa) [ABT059] (STJ197141)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2bk
ImmunogenSynthesized peptide derived from the human CK16 at the amino acid range 400-473
General Information
| Short Description | Mouse monoclonal anti-Keratin, type I cytoskeletal 16 (400-473 aa) for use in IHC, WB and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | ABT059 |
| Isotype | IgG2bk |
| Conjugation | Unconjugated |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
| Dilution Range | IHC-P 1:100-500WB 1:200-1000IF 1:100-500 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KRT16 |
| Gene ID | 3868 |
| Uniprot ID | K1C16_HUMAN |
| Immunogen | Synthesized peptide derived from the human CK16 at the amino acid range 400-473 |
| Immunogen Region | 400-473 aa |
| Specificity | The antibody can specifically recognize human CK16 protein, and shows no cross reaction with CK1, 5, 6, 7, 8, 10, 13, 14, 15, 19, 20. |
Additional Info
| Function | Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach: required for some inflammatory checkpoint for the skin barrier maintenance. |
| Protein Name | Keratin - Type I Cytoskeletal 16Cytokeratin-16Ck-16Keratin-16K16 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Keratin - Type I Cytoskeletal 16 antibodyAnti-Cytokeratin-16 antibodyAnti-Ck-16 antibodyAnti-Keratin-16 antibodyAnti-K16 antibodyAnti-KRT16 antibodyAnti-KRT16A antibody |
Information sourced from Uniprot.org