• A431 whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with anti-CK16 (ABT059) antibody. The HRP-conjugated Goat anti- mouse IgG (H + L) antibody was used to detect the antibody. Lane 1: A431Predicted band size: 51kDaObserved band size: 55kDa
  • Human cervical squamous cell carcinoma tissue was stained with Anti-Cytokeratin 16 (ABT059) Antibody
  • Human esophageal squamous cell carcinoma tissue was stained with Anti-Cytokeratin 16 (ABT059) Antibody
  • Human tonsil tissue was stained with Anti-Cytokeratin 16 (ABT059) Antibody

Anti-KRT16 antibody (400-473 aa) [ABT059] (STJ197141)

SKU:
STJ197141

Current Stock:
Host: Mouse
Applications: IHC/WB/IF
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Keratin, type I cytoskeletal 16 (400-473 aa) is suitable for use in Immunohistochemistry, Western Blot and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: ABT059
Conjugation: Unconjugated
Isotype: IgG2bk
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Dilution Range: IHC-P 1:100-500
WB 1:200-1000
IF 1:100-500
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KRT16
Gene ID: 3868
Uniprot ID: K1C16_HUMAN
Immunogen Region: 400-473 aa
Specificity: The antibody can specifically recognize human CK16 protein, and shows no cross reaction with CK1, 5, 6, 7, 8, 10, 13, 14, 15, 19, 20.
Immunogen: Synthesized peptide derived from the human CK16 at the amino acid range 400-473
Function Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach: required for some inflammatory checkpoint for the skin barrier maintenance.
Protein Name Keratin - Type I Cytoskeletal 16
Cytokeratin-16
Ck-16
Keratin-16
K16
Database Links Reactome: R-HSA-6805567
Reactome: R-HSA-6809371
Alternative Antibody Names Anti-Keratin - Type I Cytoskeletal 16 antibody
Anti-Cytokeratin-16 antibody
Anti-Ck-16 antibody
Anti-Keratin-16 antibody
Anti-K16 antibody
Anti-KRT16 antibody
Anti-KRT16A antibody

Information sourced from Uniprot.org

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