| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KRT16 |
| Gene ID: | 3868 |
| Uniprot ID: | K1C16_HUMAN |
| Immunogen Region: | 190-430 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 190-430 of human Cytokeratin 16 (KRT16) (NP_005548.2). |
| Immunogen Sequence: | LQIDNARLAADDFRTKYEHE LALRQTVEADVNGLRRVLDE LTLARTDLEMQIEGLKEELA YLRKNHEEEMLALRGQTGGD VNVEMDAAPGVDLSRILNEM RDQYEQMAEKNRRDAETWFL SKTEELNKEVASNSELVQSS RSEVTELRRVLQGLEIELQS QLSMKASLENSLEETKGRYC MQLSQIQGLIGSVEEQLAQL RCEMEQQSQEYQILLDVKTR LEQEIATYRRLLEGEDAHL |
| Tissue Specificity | Expressed in the corneal epithelium (at protein level). |
| Function | Epidermis-specific type I keratin that plays a key role in skin. Acts as a regulator of innate immunity in response to skin barrier breach: required for some inflammatory checkpoint for the skin barrier maintenance. |
| Protein Name | Keratin - Type I Cytoskeletal 16Cytokeratin-16Ck-16Keratin-16K16 |
| Database Links | Reactome: R-HSA-6805567Reactome: R-HSA-6809371 |
| Alternative Antibody Names | Anti-Keratin - Type I Cytoskeletal 16 antibodyAnti-Cytokeratin-16 antibodyAnti-Ck-16 antibodyAnti-Keratin-16 antibodyAnti-K16 antibodyAnti-KRT16 antibodyAnti-KRT16A antibody |
Information sourced from Uniprot.org