Anti-KRAS/K-Ras 2 antibody [SAA1513] (STJA0019941)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
STJA0019941
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General Information

Short DescriptionMouse monoclonal Gtpase Kras antibody for use in ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsELISA
HostMouse
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS

Product Properties

ClonalityMonoclonal
Clone IDSAA1513
IsotypeIgG2a
ConjugationUnconjugated
Concentration1 mg/mL
PurificationProtein A/G purified from cell culture supernatant
Formulation0.01M PBS, pH 7.4.
Storage InstructionSuitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months

Target Information

Gene SymbolKRAS
Gene ID3845
Uniprot IDRASK_HUMAN

Additional Info

Function Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner.
Protein Name Gtpase Kras
K-Ras 2
Ki-Ras
C-K-Ras
C-Ki-Ras Cleaved Into - Gtpase Kras - N-Terminally Processed
Database Links Reactome: R-HSA-112412
Reactome: R-HSA-1169092
Reactome: R-HSA-1236382
Reactome: R-HSA-1250196
Reactome: R-HSA-1250347
Reactome: R-HSA-1433557
Reactome: R-HSA-167044
Reactome: R-HSA-171007
Reactome: R-HSA-179812
Reactome: R-HSA-180336
Reactome: R-HSA-186763
Reactome: R-HSA-1963640
Reactome: R-HSA-210993
Reactome: R-HSA-2179392
Reactome: R-HSA-2424491
Reactome: R-HSA-2428933
Reactome: R-HSA-2871796
Reactome: R-HSA-375165
Reactome: R-HSA-4086398 P01116-2
Reactome: R-HSA-442982
Reactome: R-HSA-5218921
Reactome: R-HSA-5621575
Reactome: R-HSA-5637810
Reactome: R-HSA-5654688
Reactome: R-HSA-5654693
Reactome: R-HSA-5654699
Reactome: R-HSA-5654700
Reactome: R-HSA-5654704
Reactome: R-HSA-5654706
Reactome: R-HSA-5654712
Reactome: R-HSA-5654719
Reactome: R-HSA-5655253
Reactome: R-HSA-5655291
Reactome: R-HSA-5655302
Reactome: R-HSA-5655332
Reactome: R-HSA-5658442
Reactome: R-HSA-5673000
Reactome: R-HSA-5673001
Reactome: R-HSA-5674135
Reactome: R-HSA-5675221
Reactome: R-HSA-6802946
Reactome: R-HSA-6802948
Reactome: R-HSA-6802952
Reactome: R-HSA-6802953
Reactome: R-HSA-6802955
Reactome: R-HSA-74751
Reactome: R-HSA-8849471
Reactome: R-HSA-8851805
Reactome: R-HSA-8951936
Reactome: R-HSA-9026519
Reactome: R-HSA-9027284
Reactome: R-HSA-9028731
Reactome: R-HSA-9034864
Reactome: R-HSA-9607240
Reactome: R-HSA-9634285
Reactome: R-HSA-9634635
Reactome: R-HSA-9648002
Reactome: R-HSA-9649948
Reactome: R-HSA-9656223
Reactome: R-HSA-9664565
Reactome: R-HSA-9665348
Reactome: R-HSA-9665686
Reactome: R-HSA-9670439
Reactome: R-HSA-9673767
Reactome: R-HSA-9673770
Reactome: R-HSA-9674555
Reactome: R-HSA-9680350
Reactome: R-HSA-9703465
Reactome: R-HSA-9703648
Reactome: R-HSA-9753510
Reactome: R-HSA-9753512
Cellular Localisation Cell Membrane
Lipid-Anchor
Cytoplasmic Side
Endomembrane System
Cytoplasm
Cytosol
Isoform 2b: Cell Membrane
Alternative Antibody Names Anti-Gtpase Kras antibody
Anti-K-Ras 2 antibody
Anti-Ki-Ras antibody
Anti-C-K-Ras antibody
Anti-C-Ki-Ras Cleaved Into - Gtpase Kras - N-Terminally Processed antibody
Anti-KRAS antibody
Anti-KRAS2 antibody
Anti-RASK2 antibody

Information sourced from Uniprot.org

Citations

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