| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-KMT4 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | R03-1G7 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification: | Affinity Chromatography |
| Dilution Range: | WB 1:500-1:1000 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | DOT1L |
| Gene ID: | 84444 |
| Uniprot ID: | DOT1L_HUMAN |
| Immunogen: | A synthesized peptide derived from human KMT4/Dot1L |
| Function | Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA. |
| Protein Name | Histone-Lysine N-Methyltransferase - H3 Lysine-79 SpecificDot1-Like ProteinHistone H3-K79 MethyltransferaseH3-K79-HmtaseLysine N-Methyltransferase 4 |
| Database Links | Reactome: R-HSA-3214841 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Histone-Lysine N-Methyltransferase - H3 Lysine-79 Specific antibodyAnti-Dot1-Like Protein antibodyAnti-Histone H3-K79 Methyltransferase antibodyAnti-H3-K79-Hmtase antibodyAnti-Lysine N-Methyltransferase 4 antibodyAnti-DOT1L antibodyAnti-KIAA1814 antibodyAnti-KMT4 antibody |
Information sourced from Uniprot.org