| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Killer cell lectin-like receptor subfamily G member 1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KLRG1 |
| Gene ID: | 10219 |
| Uniprot ID: | KLRG1_HUMAN |
| Specificity: | This antibody detects endogenous levels of KLRG1 at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human KLRG1 |
| Function | Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells. |
| Protein Name | Killer Cell Lectin-Like Receptor Subfamily G Member 1C-Type Lectin Domain Family 15 Member AItim-Containing Receptor Mafa-LMafa-Like ReceptorMast Cell Function-Associated Antigen |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Killer Cell Lectin-Like Receptor Subfamily G Member 1 antibodyAnti-C-Type Lectin Domain Family 15 Member A antibodyAnti-Itim-Containing Receptor Mafa-L antibodyAnti-Mafa-Like Receptor antibodyAnti-Mast Cell Function-Associated Antigen antibodyAnti-KLRG1 antibodyAnti-CLEC15A antibodyAnti-MAFA antibodyAnti-MAFAL antibody |
Information sourced from Uniprot.org