Anti-KLK1 antibody (81-130 aa) (STJ96814)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human KLK1 at the amino acid range 81-130
General Information
| Short Description | Rabbit polyclonal anti-Kallikrein-1 (81-130 aa) for use in WB and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KLK1 |
| Gene ID | 3816 |
| Uniprot ID | KLK1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human KLK1 at the amino acid range 81-130 |
| Immunogen Region | 81-130 aa |
| Specificity | KLK1 Polyclonal Antibody detects endogenous levels of KLK1 protein. |
Additional Info
| Post Translational Modifications | The O-linked polysaccharides on Ser-93, Ser-104 and Ser-167 are probably the mucin type linked to GalNAc. In PubMed:3163150, GalNAc was detected with the corresponding peptides but not located. |
| Function | Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. (Microbial infection) Cleaves Neisseria meningitidis NHBA in saliva.Neisseria is an obligate commensal of the nasopharyngeal mucosa. |
| Protein Name | Kallikrein-1Kidney/Pancreas/Salivary Gland KallikreinTissue Kallikrein |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-9925561 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Kallikrein-1 antibodyAnti-Kidney/Pancreas/Salivary Gland Kallikrein antibodyAnti-Tissue Kallikrein antibodyAnti-KLK1 antibody |
Information sourced from Uniprot.org