Host: | Rabbit |
Applications: | WB/IHC |
Reactivity: | Human/Rat/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Kallikrein-1 (81-130 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000IHC-P 1:50-300 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | KLK1 |
Gene ID: | 3816 |
Uniprot ID: | KLK1_HUMAN |
Immunogen Region: | 81-130 aa |
Specificity: | KLK1 Polyclonal Antibody detects endogenous levels of KLK1 protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the Internal region of human KLK1 at the amino acid range 81-130 |
Post Translational Modifications | The O-linked polysaccharides on Ser-93, Ser-104 and Ser-167 are probably the mucin type linked to GalNAc. In PubMed:3163150, GalNAc was detected with the corresponding peptides but not located. |
Function | Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin. (Microbial infection) Cleaves Neisseria meningitidis NHBA in saliva.Neisseria is an obligate commensal of the nasopharyngeal mucosa. |
Protein Name | Kallikrein-1Kidney/Pancreas/Salivary Gland KallikreinTissue Kallikrein |
Database Links | Reactome: R-HSA-381426 |
Alternative Antibody Names | Anti-Kallikrein-1 antibodyAnti-Kidney/Pancreas/Salivary Gland Kallikrein antibodyAnti-Tissue Kallikrein antibodyAnti-KLK1 antibody |
Information sourced from Uniprot.org