| Post Translational Modifications | Ubiquitinated by E3 ubiquitin ligase complex formed by CUL3 and RBX1 and probably targeted for proteasome-independent degradation. Quinone-induced oxidative stress increases its ubiquitination. |
| Function | Involved in skeletal muscle development and differentiation. Regulates proliferation and differentiation of myoblasts and plays a role in myofibril assembly by promoting lateral fusion of adjacent thin fibrils into mature, wide myofibrils. Required for pseudopod elongation in transformed cells. |
| Protein Name | Kelch-Like Protein 41Kel-Like Protein 23Kelch Repeat And Btb Domain-Containing Protein 10Kelch-Related Protein 1Sarcosin |
| Database Links | Reactome: R-HSA-8951664Reactome: R-HSA-983168 |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionPseudopodiumRuffleMyofibrilSarcomereM LineSarcoplasmic Reticulum MembraneEndoplasmic Reticulum MembranePredominantly Cytoplasmic But Can Colocalize With F-Actin At The Membrane Ruffle-Like Structures At The Tips Of Transformation-Specific Pseudopodia |
| Alternative Antibody Names | Anti-Kelch-Like Protein 41 antibodyAnti-Kel-Like Protein 23 antibodyAnti-Kelch Repeat And Btb Domain-Containing Protein 10 antibodyAnti-Kelch-Related Protein 1 antibodyAnti-Sarcosin antibodyAnti-KLHL41 antibodyAnti-KBTBD10 antibodyAnti-KRP1 antibody |
Information sourced from Uniprot.org
