| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Kelch-like protein 40 (400-450 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KLHL40 |
| Gene ID: |
131377 |
| Uniprot ID: |
KLH40_HUMAN |
| Immunogen Region: |
400-450 aa |
| Specificity: |
This antibody detects endogenous levels of KBTB5 at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human KBTB5 at the amino acid range 400-450 |
| Function | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a key regulator of skeletal muscle development. The BCR(KLHL40) complex acts by mediating ubiquitination and degradation of TFDP1, thereby regulating the activity of the E2F:DP transcription factor complex. Promotes stabilization of LMOD3 by acting as a negative regulator of LMOD3 ubiquitination.the molecular process by which it negatively regulates ubiquitination of LMOD3 is however unclear. |
| Protein Name | Kelch-Like Protein 40Kelch Repeat And Btb Domain-Containing Protein 5Sarcosynapsin |
| Cellular Localisation | CytoplasmMyofibrilSarcomereA BandI Band |
| Alternative Antibody Names | Anti-Kelch-Like Protein 40 antibodyAnti-Kelch Repeat And Btb Domain-Containing Protein 5 antibodyAnti-Sarcosynapsin antibodyAnti-KLHL40 antibodyAnti-KBTBD5 antibodyAnti-SRYP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
