| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | KLHL13 |
| Gene ID: | 90293 |
| Uniprot ID: | KLH13_HUMAN |
| Immunogen Region: | 1-260 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human KLHL13 (NP_277030.2). |
| Immunogen Sequence: | MPLKWKTSSPAIWKFPVPVL KTSRSTPLSPAYISLVEEED QHMKLSLGGSEMGLSSHLQS SKAGPTRIFTSNTHSSVVLQ GFDQLRLEGLLCDVTLMPGD TDDAFPVHRVMMASASDYFK AMFTGGMKEQDLMCIKLHGV SKVGLRKIIDFIYTAKLSLN MDNLQDTLEAASFLQILPVL DFCKVFLISGVTLDNCVEVG RIANTYNLTEVDKYVNSFVL KNFPALLSTGEFLKLPFER |
| Function | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis. |
| Protein Name | Kelch-Like Protein 13Btb And Kelch Domain-Containing Protein 2 |
| Database Links | Reactome: R-HSA-8951664Reactome: R-HSA-983168 |
| Alternative Antibody Names | Anti-Kelch-Like Protein 13 antibodyAnti-Btb And Kelch Domain-Containing Protein 2 antibodyAnti-KLHL13 antibodyAnti-BKLHD2 antibodyAnti-KIAA1309 antibody |
Information sourced from Uniprot.org