Anti-KLF8 antibody (191-240 aa) (STJ93849)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human KLF8 at the amino acid range 191-240
General Information
| Short Description | Rabbit polyclonal anti-Krueppel-like factor 8 (191-240 aa) for use in IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KLF8 |
| Gene ID | 11279 |
| Uniprot ID | KLF8_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human KLF8 at the amino acid range 191-240 |
| Immunogen Region | 191-240 aa |
| Specificity | KLF8 Polyclonal Antibody detects endogenous levels of KLF8 protein. |
Additional Info
| Post Translational Modifications | Sumoylation at Lys-67 represses transcriptional activity and reduces cell cycle progression into the G(1) phase. Has no effect on subcellular location. |
| Function | Transcriptional repressor and activator. Binds to CACCC-boxes promoter elements. Also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G(1) phase as a downstream target of focal adhesion kinase (FAK). |
| Protein Name | Krueppel-Like Factor 8Basic Krueppel-Like Factor 3Zinc Finger Protein 741 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Krueppel-Like Factor 8 antibodyAnti-Basic Krueppel-Like Factor 3 antibodyAnti-Zinc Finger Protein 741 antibodyAnti-KLF8 antibodyAnti-BKLF3 antibodyAnti-ZNF741 antibody |
Information sourced from Uniprot.org