Anti-KLF2 antibody (100-200) (STJ118908)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal KLF2 (100-200) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:5000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KLF2 |
| Gene ID | 10365 |
| Uniprot ID | KLF2_HUMAN |
| Immunogen Region | 100-200 |
| Immunogen Sequence | LDAPLGPALHGRFLLAPPGR LVKAEPPEADGGGGYGCAPG LTRGPRGLKREGAPGPAASC MRGPGGRPPPPPDTPPLSPD GPARLPAPGPRASFPPPFGG P |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human KLF2 (NP_057354.1). |
Additional Info
| Post Translational Modifications | Ubiquitinated. Polyubiquitination involves WWP1 and leads to proteasomal degradation of this protein. |
| Function | Transcription factor that binds to the CACCC box in the promoter of target genes such as HBB/beta globin or NOV and activates their transcription. Might be involved in transcriptional regulation by modulating the binding of the RARA nuclear receptor to RARE DNA elements. |
| Protein Name | Krueppel-Like Factor 2Lung Krueppel-Like Factor |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Krueppel-Like Factor 2 antibodyAnti-Lung Krueppel-Like Factor antibodyAnti-KLF2 antibodyAnti-LKLF antibody |
Information sourced from Uniprot.org