| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:5000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KLF2 |
| Gene ID: | 10365 |
| Uniprot ID: | KLF2_HUMAN |
| Immunogen Region: | 100-200 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human KLF2 (NP_057354.1). |
| Immunogen Sequence: | LDAPLGPALHGRFLLAPPGR LVKAEPPEADGGGGYGCAPG LTRGPRGLKREGAPGPAASC MRGPGGRPPPPPDTPPLSPD GPARLPAPGPRASFPPPFGG P |
| Post Translational Modifications | Ubiquitinated. Polyubiquitination involves WWP1 and leads to proteasomal degradation of this protein. |
| Function | Transcription factor that binds to the CACCC box in the promoter of target genes such as HBB/beta globin or NOV and activates their transcription. Might be involved in transcriptional regulation by modulating the binding of the RARA nuclear receptor to RARE DNA elements. |
| Protein Name | Krueppel-Like Factor 2Lung Krueppel-Like Factor |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Krueppel-Like Factor 2 antibodyAnti-Lung Krueppel-Like Factor antibodyAnti-KLF2 antibodyAnti-LKLF antibody |
Information sourced from Uniprot.org