Anti-KLC1 antibody [R02-9G3] (STJA0037379)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human KLC1
General Information
| Short Description | Rabbit monoclonal anti-KLC1 for use in WB, IHC-P, ICC, IF, IP and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ICC/IF/IP/FC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R02-9G3 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200IP 1:50FC 1:50-1:100 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | KLC1 |
| Gene ID | 3831 |
| Uniprot ID | KLC1_HUMAN |
| Immunogen | A synthesized peptide derived from human KLC1 |
Additional Info
| Tissue Specificity | Found in a variety of tissues. Mostly abundant in brain and spine. |
| Post Translational Modifications | Phosphorylation at Ser-460 by ERK inhibits interaction with CLSTN1 and localization to cytoplasmic vesicles. |
| Function | Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity. |
| Protein Name | Kinesin Light Chain 1Klc 1 |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-5625970Reactome: R-HSA-6811434Reactome: R-HSA-9725370Reactome: R-HSA-983189 |
| Cellular Localisation | Cell ProjectionGrowth ConeCytoplasmic VesicleCytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Kinesin Light Chain 1 antibodyAnti-Klc 1 antibodyAnti-KLC1 antibodyAnti-KLC antibodyAnti-KNS2 antibody |
Information sourced from Uniprot.org