Anti-KIRREL2 antibody (STJ192117)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Kin of IRRE-like protein 2 for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KIRREL2 |
| Gene ID | 84063 |
| Uniprot ID | KIRR2_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | KIRR2 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | N-glycosylated. The extracellular domain is cleaved leading to the generation of a soluble fragment and a membrane-bound C-terminal fragment, which is further cleaved by gamma-secretase. |
| Function | May regulate basal insulin secretion. |
| Protein Name | Kin Of Irre-Like Protein 2Kin Of Irregular Chiasm-Like Protein 2Nephrin-Like Protein 3 |
| Database Links | Reactome: R-HSA-373753 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinLocalized Along The Sites Of The Cell ContactsColocalizes With E-Cadherin And Beta-Catenin |
| Alternative Antibody Names | Anti-Kin Of Irre-Like Protein 2 antibodyAnti-Kin Of Irregular Chiasm-Like Protein 2 antibodyAnti-Nephrin-Like Protein 3 antibodyAnti-KIRREL2 antibodyAnti-NEPH3 antibodyAnti-UNQ5827 antibodyAnti-PRO19646 antibody |
Information sourced from Uniprot.org