| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KIR2DL1 |
| Gene ID: | 3802 |
| Uniprot ID: | KI2L1_HUMAN |
| Immunogen Region: | 22-270 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-270 of human KIR2DL1 (XP_003403624.1). |
| Immunogen Sequence: | HEGVHRKPSLLAHPGRLVKS EETVILQCWSDVRFEHFLLH REGKFKDTLHLIGEHHDGVS KANFSIGPMMQDLAGTYRCY GSVTHSPYQLSAPSDPLDIV ITGLYEKPSLSAQPGPTVLA GESVTLSCSSRSSYDMYHLS REGEAHECRFSAGPKVNGTF QADFPLGPATHGGTYRCFGS FRDSPYEWSNSSDPLLVSVT GNPSNSWPSPTEPSSKTERM FHHVGQACLKLPTSSDPTV |
| Tissue Specificity | Expressed by NK cells. |
| Function | Receptor on natural killer (NK) cells for some HLA-C alleles such as w4 and w6. Inhibits the activity of NK cells thus preventing cell lysis. |
| Protein Name | Killer Cell Immunoglobulin-Like Receptor 2dl1Cd158 Antigen-Like Family Member ANatural Killer-Associated Transcript 1Nkat-1P58 Natural Killer Cell Receptor Clones Cl-42/47.11P58 Nk Receptor Cl-42/47.11P58.1 Mhc Class-I-Specific Nk ReceptorCd Antigen Cd158a |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Killer Cell Immunoglobulin-Like Receptor 2dl1 antibodyAnti-Cd158 Antigen-Like Family Member A antibodyAnti-Natural Killer-Associated Transcript 1 antibodyAnti-Nkat-1 antibodyAnti-P58 Natural Killer Cell Receptor Clones Cl-42/47.11 antibodyAnti-P58 Nk Receptor Cl-42/47.11 antibodyAnti-P58.1 Mhc Class-I-Specific Nk Receptor antibodyAnti-Cd Antigen Cd158a antibodyAnti-KIR2DL1 antibodyAnti-CD158A antibodyAnti-NKAT1 antibody |
Information sourced from Uniprot.org