Anti-Kinesin light chain 1 antibody (450-550) [S1MR] (STJ11102981)

Name: Anti-Kinesin light chain 1 antibody (450-550) [S1MR] (STJ11102981)
SKU: STJ11102981
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⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11102981

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Short Description	Rabbit monoclonal Kinesin light chain 1 (KLC1) (450-550) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	S1MR
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	KLC1
Gene ID	3831
Uniprot ID	KLC1_HUMAN
Immunogen Region	450-550
Immunogen Sequence	GGWYKACKVDSPTVTTTLKN LGALYRRQGKFEAAETLEEA AMRSRKQGLDNVHKQRVAEV LNDPENMEKRRSRESLNVDV VKYESGPDGGEEVSMSVEWN G
Specificity	A synthetic peptide corresponding to a sequence within amino acids 450-550 of human Kinesin light chain 1 (KLC1) (Q07866).

Tissue Specificity	Found in a variety of tissues. Mostly abundant in brain and spine.
Post Translational Modifications	Phosphorylation at Ser-460 by ERK inhibits interaction with CLSTN1 and localization to cytoplasmic vesicles.
Function	Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity.
Protein Name	Kinesin Light Chain 1 Klc 1
Database Links	Reactome: R-HSA-2132295 Reactome: R-HSA-5625970 Reactome: R-HSA-6811434 Reactome: R-HSA-9725370 Reactome: R-HSA-983189
Cellular Localisation	Cell Projection Growth Cone Cytoplasmic Vesicle Cytoplasm Cytoskeleton
Alternative Antibody Names	Anti-Kinesin Light Chain 1 antibody Anti-Klc 1 antibody Anti-KLC1 antibody Anti-KLC antibody Anti-KNS2 antibody

Information sourced from Uniprot.org