Anti-Kinesin antibody (STJ16101149)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
Immunogenstalk domain of human kinesin (aa 331-906) expressed in E. coli (FKHC3)
General Information
| Short Description | Rabbit polyclonal anti-Kinesin for use in WB and ICC in Mouse, Pig and Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ICC |
| Host | Rabbit |
| Reactivity | Mouse/Pig/Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity purified |
| Formulation | Phosphate buffered saline (PBS) solution with 15 mM sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Immunogen | stalk domain of human kinesin (aa 331-906) expressed in E. coli (FKHC3) |
Additional Info
| Background | Kinesin belongs to the group of microtubule-associated motor proteins known to convert chemical energy released from nucleoside triphosphates (preferentially from ATP) into mechanical energy. Conventional kinesin, member of the kinesin superfamily comprising more than 100 proteins, is involved in the anterograde vesicle transport in neuronal cells. Kinesin purified from mammalian brain homogenates is a heterotetramer consisting of two heavy (120 to 130 kDa) and two light chains (60 to 70 kDa) , resulting in a molecular mass about 400 kDa. Each heavy chain contains an N-terminal globular motordomain with both a microtubule-binding site and an ATPase active center, stalk region responsible for heavy chain dimerization and finally C-terminal globular tail domain, which is implicated in cargo binding. Light chains may have a regulatory function. |
Information sourced from Uniprot.org