Anti-KIF2B antibody (STJA0009601)

SKU:
STJA0009601
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-Kinesin-like protein KIF2B for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:KIF2B
Gene ID:84643
Uniprot ID:KIF2B_HUMAN
Immunogen:Synthesized peptide derived from human KIF2B
Specificity:This antibody detects endogenous levels of KIF2B at Human, Mouse, Rat
Post Translational Modifications Phosphorylation at Thr-125 by PLK1 is required for activity in the correction of kinetochore-microtubules attachment errors, while phosphorylation at Ser-204 also by PLK1 is required for the kinetochore localization and activity in prometaphase.
Function Plus end-directed microtubule-dependent motor required for spindle assembly and chromosome movement. Has microtubule depolymerization activity. Plays a role in chromosome congression.
Protein Name Kinesin-Like Protein Kif2b
Database Links Reactome: R-HSA-141444
Reactome: R-HSA-2132295
Reactome: R-HSA-2467813
Reactome: R-HSA-2500257
Reactome: R-HSA-5663220
Reactome: R-HSA-6811434
Reactome: R-HSA-68877
Reactome: R-HSA-9648025
Reactome: R-HSA-983189
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Spindle
Chromosome
Centromere
Kinetochore
Association With Kinetochore Is Transient
Alternative Antibody Names Anti-Kinesin-Like Protein Kif2b antibody
Anti-KIF2B antibody

Information sourced from Uniprot.org