| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
KIF23 |
| Gene ID: |
9493 |
| Uniprot ID: |
KIF23_HUMAN |
| Immunogen Region: |
700-950 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 700-950 of human KIF23 (NP_612565.1). |
| Immunogen Sequence: |
NGQQLMSQPQLHRRSNSCSS ISVASCISEWEQKIPTYNTP LKVTSIARRRQQEPGQSKTC IVSDRRRGMYWTEGREVVPT FRNEIEIEEDHCGRLLFQPD QNAPPIRLRHRRSRSAGDRW VDHKPASNMQTETVMQPHVP HAITVSVANEKALAKCEKYM LTHQELASDGEIETKLIKGD IYKTRGGGQSVQFTDIETLK QESPNGSRKRRSSTVAPAQP DGAESEWTDVETRCSVAVE |
| Tissue Specificity | Widely expressed. |
| Post Translational Modifications | Ubiquitinated. Deubiquitinated by USP8/UBPY. |
| Function | Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro. |
| Protein Name | Kinesin-Like Protein Kif23Kinesin-Like Protein 5Mitotic Kinesin-Like Protein 1 |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-6811434Reactome: R-HSA-68884Reactome: R-HSA-983189 |
| Cellular Localisation | NucleusCytoplasmCytoskeletonSpindleMidbodyMidbody RingLocalizes To The Interzone Of Mitotic SpindlesDetected At The Midbody During Later Stages Of Mitotic Cytokinesis |
| Alternative Antibody Names | Anti-Kinesin-Like Protein Kif23 antibodyAnti-Kinesin-Like Protein 5 antibodyAnti-Mitotic Kinesin-Like Protein 1 antibodyAnti-KIF23 antibodyAnti-KNSL5 antibodyAnti-MKLP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
