| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | KIF21B |
| Gene ID: | 23046 |
| Uniprot ID: | KI21B_HUMAN |
| Immunogen Region: | 800-1000 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 800-1000 of human KIF21B (NP_001239029.1). |
| Immunogen Sequence: | ALESQKRQQEMVLRRKTQEV SALRRLAKPMSERVAGRAGL KPPMLDSGAEVSASTTSSEA ESGARSVSSIVRQWNRKINH FLGDHPAPTVNGTRPARKKF QKKGASQSFSKAARLKWQSL ERRIIDIVMQRMTIVNLEAD MERLIKKREELFLLQEALRR KRERLQAESPEEEKGLQELA EEIEVLAANIDYINDGITDC Q |
| Function | Plus-end directed microtubule-dependent motor protein which displays processive activity. Is involved in regulation of microtubule dynamics, synapse function and neuronal morphology, including dendritic tree branching and spine formation. Plays a role in lerning and memory. Involved in delivery of gamma-aminobutyric acid (GABA(A)) receptor to cell surface. |
| Protein Name | Kinesin-Like Protein Kif21b |
| Database Links | Reactome: R-HSA-6811434Reactome: R-HSA-983189 |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionDendriteGrowth ConeAxonCytoplasmic Vesicle |
| Alternative Antibody Names | Anti-Kinesin-Like Protein Kif21b antibodyAnti-KIF21B antibodyAnti-KIAA0449 antibody |
Information sourced from Uniprot.org