Host: | Rabbit |
Applications: | WB/IHC/IF/ELISA |
Reactivity: | Human/Rat/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Kinesin-like protein KIF20A (501-550 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | KIF20A |
Gene ID: | 10112 |
Uniprot ID: | KI20A_HUMAN |
Immunogen Region: | 501-550 aa |
Specificity: | KIF20A Polyclonal Antibody detects endogenous levels of KIF20A protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the human KIF20A at the amino acid range 501-550 |
Function | Mitotic kinesin required for chromosome passenger complex (CPC)-mediated cytokinesis. Following phosphorylation by PLK1, involved in recruitment of PLK1 to the central spindle. Interacts with guanosine triphosphate (GTP)-bound forms of RAB6A and RAB6B. May act as a motor required for the retrograde RAB6 regulated transport of Golgi membranes and associated vesicles along microtubules. Has a microtubule plus end-directed motility. |
Protein Name | Kinesin-Like Protein Kif20aGg10_2Mitotic Kinesin-Like Protein 2Mklp2Rab6-Interacting Kinesin-Like ProteinRabkinesin-6 |
Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-6811434Reactome: R-HSA-68884Reactome: R-HSA-983189 |
Cellular Localisation | Golgi ApparatusCytoplasmCytoskeletonSpindleLocalizes To The Spindle Midzone During Anaphase And Telophase |
Alternative Antibody Names | Anti-Kinesin-Like Protein Kif20a antibodyAnti-Gg10_2 antibodyAnti-Mitotic Kinesin-Like Protein 2 antibodyAnti-Mklp2 antibodyAnti-Rab6-Interacting Kinesin-Like Protein antibodyAnti-Rabkinesin-6 antibodyAnti-KIF20A antibodyAnti-MKLP2 antibodyAnti-RAB6KIFL antibody |
Information sourced from Uniprot.org