| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | PUM3 |
| Gene ID: | 9933 |
| Uniprot ID: | PUM3_HUMAN |
| Immunogen Region: | 1-220 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human KIAA0020 (NP_055693.4). |
| Immunogen Sequence: | MEVKGKKQFTGKSTKTAQEK NRFHKNSDSGSSKTFPTRKV AKEGGPKVTSRNFEKSITKL GKKGVKQFKNKQQGDKSPKN KFQPANKFNKKRKFQPDGRS DESAAKKPKWDDFKKKKKEL KQSRQLSDKTNYDIVVRAKQ MWEILRRKDCDKEKRVKLMS DLQKLIQGKIKTIAFAHDST RVIQCYIQYGNEEQRKQAFE ELRDDLVELSKAKYSRNIVK |
| Tissue Specificity | Widely expressed. |
| Function | Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress. Binds to double-stranded RNA or DNA without sequence specificity. Involved in development of the eye and of primordial germ cells. |
| Protein Name | Pumilio Homolog 3Hbv X-Transactivated Gene 5 ProteinHbv Xag-Transactivated Protein 5Minor Histocompatibility Antigen Ha-8Hla-Ha8 |
| Cellular Localisation | NucleusNucleolusNucleoplasmChromosomeLocalizes Predominantly In The Nucleolus With Minor Punctate Signals In The Nucleoplasm |
| Alternative Antibody Names | Anti-Pumilio Homolog 3 antibodyAnti-Hbv X-Transactivated Gene 5 Protein antibodyAnti-Hbv Xag-Transactivated Protein 5 antibodyAnti-Minor Histocompatibility Antigen Ha-8 antibodyAnti-Hla-Ha8 antibodyAnti-PUM3 antibodyAnti-cPERP-C antibodyAnti-KIAA0020 antibodyAnti-PUF-A antibodyAnti-XTP5 antibody |
Information sourced from Uniprot.org