| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Lysine-specific demethylase 4D demethylase 4D (400-480 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KDM4D |
| Gene ID: | 55693 |
| Uniprot ID: | KDM4D_HUMAN |
| Immunogen Region: | 400-480 aa |
| Specificity: | KDM4D Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 400-480 |
| Function | Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. |
| Protein Name | Lysine-Specific Demethylase 4dJmjc Domain-Containing Histone Demethylation Protein 3dJumonji Domain-Containing Protein 2dHistone H3-Trimethyl-L-Lysine(9 Demethylase 4d |
| Database Links | Reactome: R-HSA-3214842 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Lysine-Specific Demethylase 4d antibodyAnti-Jmjc Domain-Containing Histone Demethylation Protein 3d antibodyAnti-Jumonji Domain-Containing Protein 2d antibodyAnti-Histone H3-Trimethyl-L-Lysine(9 Demethylase 4d antibodyAnti-KDM4D antibodyAnti-JHDM3D antibodyAnti-JMJD2D antibody |
Information sourced from Uniprot.org