| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KDM3B |
| Gene ID: | 51780 |
| Uniprot ID: | KDM3B_HUMAN |
| Immunogen Region: | 400-600 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 400-600 of human KDM3B (NP_057688.2). |
| Immunogen Sequence: | GAENKEAGKTLEQVGQGIVA SAAVVTTASSTPNTVRISDT GLAAGTVPEKQKGSRSQASG ENSRNSILASSGFGAPLPSS SQPLTFGSGRSQSNGVLATE NKPLGFSFGCSSAQEAQKDT DLSKNLFFQCMSQTLPTSNY FTTVSESLADDSSSRDSFKQ SLESLSSGLCKGRSVLGTDT KPGSKAGSSVDRKVPAESMP T |
| Tissue Specificity | Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver. |
| Function | Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity. |
| Protein Name | Lysine-Specific Demethylase 3bJmjc Domain-Containing Histone Demethylation Protein 2bJumonji Domain-Containing Protein 1bNuclear Protein 5qncaHistone H3-Dimethyl-L-Lysine(9 Demethylase 3b |
| Database Links | Reactome: R-HSA-3214842 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Lysine-Specific Demethylase 3b antibodyAnti-Jmjc Domain-Containing Histone Demethylation Protein 2b antibodyAnti-Jumonji Domain-Containing Protein 1b antibodyAnti-Nuclear Protein 5qnca antibodyAnti-Histone H3-Dimethyl-L-Lysine(9 Demethylase 3b antibodyAnti-KDM3B antibodyAnti-C5orf7 antibodyAnti-JHDM2B antibodyAnti-JMJD1B antibodyAnti-KIAA1082 antibody |
Information sourced from Uniprot.org