| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-KDM3B (400-600) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KDM3B |
| Gene ID: |
51780 |
| Uniprot ID: |
KDM3B_HUMAN |
| Immunogen Region: |
400-600 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 400-600 of human KDM3B (NP_057688.2). |
| Immunogen Sequence: |
GAENKEAGKTLEQVGQGIVA SAAVVTTASSTPNTVRISDT GLAAGTVPEKQKGSRSQASG ENSRNSILASSGFGAPLPSS SQPLTFGSGRSQSNGVLATE NKPLGFSFGCSSAQEAQKDT DLSKNLFFQCMSQTLPTSNY FTTVSESLADDSSSRDSFKQ SLESLSSGLCKGRSVLGTDT KPGSKAGSSVDRKVPAESMP T |
| Tissue Specificity | Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver. |
| Function | Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity. |
| Protein Name | Lysine-Specific Demethylase 3bJmjc Domain-Containing Histone Demethylation Protein 2bJumonji Domain-Containing Protein 1bNuclear Protein 5qncaHistone H3-Dimethyl-L-Lysine(9 Demethylase 3b |
| Database Links | Reactome: R-HSA-3214842 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Lysine-Specific Demethylase 3b antibodyAnti-Jmjc Domain-Containing Histone Demethylation Protein 2b antibodyAnti-Jumonji Domain-Containing Protein 1b antibodyAnti-Nuclear Protein 5qnca antibodyAnti-Histone H3-Dimethyl-L-Lysine(9 Demethylase 3b antibodyAnti-KDM3B antibodyAnti-C5orf7 antibodyAnti-JHDM2B antibodyAnti-JMJD1B antibodyAnti-KIAA1082 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
