| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
KDELR1 |
| Gene ID: |
10945 |
| Uniprot ID: |
ERD21_HUMAN |
| Immunogen Region: |
40-100 aa |
| Specificity: |
A synthetic peptide corresponding to a sequence within amino acids 40-100 of human KDELR1 (NP_006792.1). |
| Immunogen Sequence: |
FAVVFTARYLDLFTNYISLY NTCMKVVYIACSFTTVWLIY SKFKATYDGNHDTFRVEFLV V |
| Post Translational Modifications | Phosphorylation by PKA at Ser-209 is required for endoplasmic reticulum retention function. |
| Function | Receptor for the C-terminal sequence motif K-D-E-L that is present on endoplasmic reticulum resident proteins and that mediates their recycling from the Golgi back to the endoplasmic reticulum. |
| Protein Name | Er Lumen Protein-Retaining Receptor 1Kdel Endoplasmic Reticulum Protein Retention Receptor 1Kdel Receptor 1Putative Mapk-Activating Protein Pm23 |
| Database Links | Reactome: R-HSA-6807878Reactome: R-HSA-6811434 |
| Cellular Localisation | Golgi Apparatus MembraneMulti-Pass Membrane ProteinCytoplasmic VesicleCopi-Coated Vesicle MembraneEndoplasmic Reticulum MembraneEndoplasmic Reticulum-Golgi Intermediate Compartment MembraneLocalized In The Golgi In The Absence Of Bound Proteins With The Sequence Motif K-D-E-LTrafficks Back To The Endoplasmic Reticulum Together With Cargo Proteins Containing The Sequence Motif K-D-E-L |
| Alternative Antibody Names | Anti-Er Lumen Protein-Retaining Receptor 1 antibodyAnti-Kdel Endoplasmic Reticulum Protein Retention Receptor 1 antibodyAnti-Kdel Receptor 1 antibodyAnti-Putative Mapk-Activating Protein Pm23 antibodyAnti-KDELR1 antibodyAnti-ERD2.1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
