Anti-KCTD13 antibody (STJA0004638)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenFusion protein of human KCTD13
General Information
| Short Description | Rabbit polyclonal anti-Btb/Poz Domain-Containing Adapter For Cul3-Mediated Rhoa Degradation Protein 1 for use in IHC and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.96 mg/mL |
| Purification | Antigen affinity purification |
| Dilution Range | IHC 1:50-1:300 |
| Formulation | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | KCTD13 |
| Gene ID | 253980 |
| Uniprot ID | BACD1_HUMAN |
| Immunogen | Fusion protein of human KCTD13 |
Additional Info
| Tissue Specificity | Expressed in a wide variety of tissues. |
| Function | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for synaptic transmission. The BCR(KCTD13) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome Degradation of RHOA regulates the actin cytoskeleton and promotes synaptic transmission. |
| Protein Name | Btb/Poz Domain-Containing Adapter For Cul3-Mediated Rhoa Degradation Protein 1Hbacurd1Btb/Poz Domain-Containing Protein Kctd13Polymerase Delta-Interacting Protein 1Tnfaip1-Like Protein |
| Database Links | Reactome: R-HSA-9696264Reactome: R-HSA-9696270 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Btb/Poz Domain-Containing Adapter For Cul3-Mediated Rhoa Degradation Protein 1 antibodyAnti-Hbacurd1 antibodyAnti-Btb/Poz Domain-Containing Protein Kctd13 antibodyAnti-Polymerase Delta-Interacting Protein 1 antibodyAnti-Tnfaip1-Like Protein antibodyAnti-KCTD13 antibodyAnti-BACURD1 antibodyAnti-PDIP1 antibodyAnti-POLDIP1 antibodyAnti-FKSG86 antibodyAnti-PP6832 antibody |
Information sourced from Uniprot.org