| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-KCNT1 for use in IHC and WB in Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A dilution of 1:2000 to 1:3000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | Kcnt1 |
| Gene ID: | 227632 |
| Uniprot ID: | KCNT1_MOUSE |
| Specificity: | Specific for KCNT1. |
| Immunogen: | A synthetic peptide from mouse KCNT1 conjugated to blue carrier protein was used as the antigen. |
| Post Translational Modifications | Phosphorylated by protein kinase C. Phosphorylation of the C-terminal domain increases channel activity. |
| Function | Sodium-activated K(+) channel. Acts as an important mediator of neuronal membrane excitability. Contributes to the delayed outward currents. Regulates neuronal bursting in sensory neurons. Contributes to synaptic development and plasticity. |
| Protein Name | Potassium Channel Subfamily T Member 1 |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Potassium Channel Subfamily T Member 1 antibodyAnti-Kcnt1 antibodyAnti-Kiaa1422 antibodyAnti-Slack antibodyAnti-Slo2.2 antibody |
Information sourced from Uniprot.org
