| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human/Marmoset |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-KCNT1 is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A dilution of 1:3000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | KCNT1 |
| Gene ID: | 57582 |
| Uniprot ID: | KCNT1_HUMAN |
| Specificity: | Specific for KCNT1. |
| Immunogen: | A synthetic peptide from human KCNT1 conjugated to blue carrier protein was used as the antigen. |
| Post Translational Modifications | Phosphorylated by protein kinase C. Phosphorylation of the C-terminal domain increases channel activity. |
| Function | Outwardly rectifying potassium channel subunit that may coassemble with other Slo-type channel subunits. Activated by high intracellular sodium or chloride levels. Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. May be regulated by calcium in the absence of sodium ions (in vitro). |
| Protein Name | Potassium Channel Subfamily T Member 1Kca4.1 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Potassium Channel Subfamily T Member 1 antibodyAnti-Kca4.1 antibodyAnti-KCNT1 antibodyAnti-KIAA1422 antibody |
Information sourced from Uniprot.org