• Western blot analysis of lysates from HepG2 cells, using KCNN4 Antibody. The lane on the right is blocked with the synthesized peptide.

Anti-KCNN4 antibody (331-380 aa) (STJ93663)

SKU:
STJ93663

Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Intermediate conductance calcium-activated potassium channel protein 4 (331-380 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KCNN4
Gene ID: 3783
Uniprot ID: KCNN4_HUMAN
Immunogen Region: 331-380 aa
Specificity: IK1 Polyclonal Antibody detects endogenous levels of IK1 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human KCNN4 at the amino acid range 331-380
Post Translational Modifications Phosphorylation at His-358 by NDKB activates the channel, and conversely it's dephosphorylation by PHPT1 inhibits the channel.
Function Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. Plays a role in the late stages of EGF-induced macropinocytosis.
Protein Name Intermediate Conductance Calcium-Activated Potassium Channel Protein 4
Sk4
Skca 4
Skca4
Ikca1
Ik1
Kca3.1
Kca4
Putative Gardos Channel
Database Links Reactome: R-HSA-1296052
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Intermediate Conductance Calcium-Activated Potassium Channel Protein 4 antibody
Anti-Sk4 antibody
Anti-Skca 4 antibody
Anti-Skca4 antibody
Anti-Ikca1 antibody
Anti-Ik1 antibody
Anti-Kca3.1 antibody
Anti-Kca4 antibody
Anti-Putative Gardos Channel antibody
Anti-KCNN4 antibody
Anti-IK1 antibody
Anti-IKCA1 antibody
Anti-KCA4 antibody
Anti-SK4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance