Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Calcium-activated potassium channel subunit beta-2beta-2 (151-200 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
KCNMB2 |
Gene ID: |
10242 |
Uniprot ID: |
KCMB2_HUMAN |
Immunogen Region: |
151-200 aa |
Specificity: |
MaxiK Beta 2 Polyclonal Antibody detects endogenous levels of MaxiK Beta 2 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human KCNMB2 at the amino acid range 151-200 |
Post Translational Modifications | N-glycosylated. |
Function | Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers rapid and complete inactivation of KCNMA1 channel complex. May participate in KCNMA1 inactivation in chromaffin cells of the adrenal gland or in hippocampal CA1 neurons. |
Protein Name | Calcium-Activated Potassium Channel Subunit Beta-2Bk Channel Subunit Beta-2Bkbeta2Hbeta2Calcium-Activated Potassium Channel - Subfamily M Subunit Beta-2Charybdotoxin Receptor Subunit Beta-2Hbeta3K(Vcabeta-2Maxi K Channel Subunit Beta-2Slo-Beta-2 |
Database Links | Reactome: R-HSA-1296052Reactome: R-HSA-418457 |
Cellular Localisation | MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-Calcium-Activated Potassium Channel Subunit Beta-2 antibodyAnti-Bk Channel Subunit Beta-2 antibodyAnti-Bkbeta2 antibodyAnti-Hbeta2 antibodyAnti-Calcium-Activated Potassium Channel - Subfamily M Subunit Beta-2 antibodyAnti-Charybdotoxin Receptor Subunit Beta-2 antibodyAnti-Hbeta3 antibodyAnti-K(Vcabeta-2 antibodyAnti-Maxi K Channel Subunit Beta-2 antibodyAnti-Slo-Beta-2 antibodyAnti-KCNMB2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance