| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-KCNK5 (C-Term) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | KCNK5 |
| Gene ID: | 8645 |
| Uniprot ID: | KCNK5_HUMAN |
| Immunogen Region: | C-Term |
| Specificity: | Specific for KCNK5. |
| Immunogen: | A synthetic peptide from the c-terminal region of human KCNK5 (TASK2) conjugated to an immunogenic carrier protein was used as the antigen. |
| Function | K(+) channel that conducts voltage-dependent outward rectifying currents upon membrane depolarization. Voltage sensing is coupled to K(+) electrochemical gradient in an 'ion flux gating' mode where outward but not inward ion flow opens the gate. Homo- and heterodimerizes to form functional channels with distinct regulatory and gating properties. |
| Protein Name | Potassium Channel Subfamily K Member 5Acid-Sensitive Potassium Channel Protein Task-2Twik-Related Acid-Sensitive K(+ Channel 2 |
| Database Links | Reactome: R-HSA-5576886 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Potassium Channel Subfamily K Member 5 antibodyAnti-Acid-Sensitive Potassium Channel Protein Task-2 antibodyAnti-Twik-Related Acid-Sensitive K(+ Channel 2 antibodyAnti-KCNK5 antibodyAnti-TASK2 antibody |
Information sourced from Uniprot.org