| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-KCNJ8 (325-424) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KCNJ8 |
| Gene ID: |
3764 |
| Uniprot ID: |
KCNJ8_HUMAN |
| Immunogen Region: |
325-424 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 325-424 of human KCNJ8 (NP_004973.1). |
| Immunogen Sequence: |
VSIVTEEEGVYSVDYSKFGN TVKVAAPRCSARELDEKPSI LIQTLQKSELSHQNSLRKRN SMRRNNSMRRNNSIRRNNSS LMVPKVQFMTPEGNQNTSES |
| Tissue Specificity | Predominantly detected in fetal and adult heart. |
| Function | This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium.as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium. |
| Protein Name | Atp-Sensitive Inward Rectifier Potassium Channel 8Inward Rectifier K(+ Channel Kir6.1Potassium Channel - Inwardly Rectifying Subfamily J Member 8Ukatp-1 |
| Database Links | Reactome: R-HSA-1296025 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Atp-Sensitive Inward Rectifier Potassium Channel 8 antibodyAnti-Inward Rectifier K(+ Channel Kir6.1 antibodyAnti-Potassium Channel - Inwardly Rectifying Subfamily J Member 8 antibodyAnti-Ukatp-1 antibodyAnti-KCNJ8 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and Cytokeratin 20 (Cytokeratin 20 (KRT20) ) knockout (KO) HeLa cells, using [KO Validated] Cytokeratin 20 (KRT20) Rabbit polyclonal antibody (STJ119970) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/98755/382808/STJ119970_1__87130.1713151301.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and Cytokeratin 20 (Cytokeratin 20 (KRT20) ) knockout (KO) HeLa cells, using [KO Validated] Cytokeratin 20 (KRT20) Rabbit polyclonal antibody (STJ119970) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
