Anti-KCNJ5 antibody (370-419 aa) (STJ93842)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human KCNJ5 at the amino acid range 370-419
General Information
| Short Description | Rabbit polyclonal anti-G protein-activated inward rectifier potassium channel 4 channel Kir3.4 (370-419 aa) for use in WB and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KCNJ5 |
| Gene ID | 3762 |
| Uniprot ID | KCNJ5_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human KCNJ5 at the amino acid range 370-419 |
| Immunogen Region | 370-419 aa |
| Specificity | KIR3.4 Polyclonal Antibody detects endogenous levels of KIR3.4 protein. |
Additional Info
| Function | Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium.as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium. This potassium channel is controlled by G proteins. |
| Protein Name | G Protein-Activated Inward Rectifier Potassium Channel 4Girk-4Cardiac Inward RectifierCirHeart Katp ChannelInward Rectifier K(+ Channel Kir3.4Irk-4Katp-1Potassium Channel - Inwardly Rectifying Subfamily J Member 5 |
| Database Links | Reactome: R-HSA-1296041Reactome: R-HSA-997272 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-G Protein-Activated Inward Rectifier Potassium Channel 4 antibodyAnti-Girk-4 antibodyAnti-Cardiac Inward Rectifier antibodyAnti-Cir antibodyAnti-Heart Katp Channel antibodyAnti-Inward Rectifier K(+ Channel Kir3.4 antibodyAnti-Irk-4 antibodyAnti-Katp-1 antibodyAnti-Potassium Channel - Inwardly Rectifying Subfamily J Member 5 antibodyAnti-KCNJ5 antibodyAnti-GIRK4 antibody |
Information sourced from Uniprot.org