| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Potassium voltage-gated channel subfamily E member 4 (90-170 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | KCNE4 |
| Gene ID: | 23704 |
| Uniprot ID: | KCNE4_HUMAN |
| Immunogen Region: | 90-170 aa |
| Specificity: | KCNE4 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 90-170 |
| Function | Ancillary protein that functions as a regulatory subunit of the voltage-gated potassium (Kv) channel complex composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunits. KCNE4 beta subunit modulates the gating kinetics and enhances stability of the channel complex. Associates with KCNQ1/KVLTQ1 alpha subunit to inhibit potassium currents. Isoform 2: May inhibit KCNQ4-mediated potassium currents. |
| Protein Name | Potassium Voltage-Gated Channel Subfamily E Member 4Mink-Related Peptide 3Mirp3Minimum Potassium Ion Channel-Related Peptide 3Potassium Channel Subunit Beta Mirp3 |
| Database Links | Reactome: R-HSA-5576890Reactome: R-HSA-5576893 |
| Cellular Localisation | MembraneSingle-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Potassium Voltage-Gated Channel Subfamily E Member 4 antibodyAnti-Mink-Related Peptide 3 antibodyAnti-Mirp3 antibodyAnti-Minimum Potassium Ion Channel-Related Peptide 3 antibodyAnti-Potassium Channel Subunit Beta Mirp3 antibodyAnti-KCNE4 antibody |
Information sourced from Uniprot.org