• Western blot analysis of extracts of various cell lines, using KCND1 antibody (STJ118129) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-KCND1 antibody (488-647) (STJ118129)

SKU:
STJ118129

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-KCND1 (488-647) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: KCND1
Gene ID: 3750
Uniprot ID: KCND1_HUMAN
Immunogen Region: 488-647
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 488-647 of human KCND1 (NP_004970.3).
Immunogen Sequence: TTCHEFTDELTFSEALGAVS PGGRTSRSTSVSSQPVGPGS LLSSCCPRRAKRRAIRLANS TASVSRGSMQELDMLAGLRR SHAPQSRSSLNAKPHDSLDL NCDSRDFVAAIISIPTPPAN TPDESQPSSPGGGGRAGSTL RNSSLGTPCLFPETVKISSL
Tissue Specificity Widely expressed. Highly expressed in brain, in particular in cerebellum and thalamus.detected at lower levels in the other parts of the brain.
Function Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits.
Protein Name Potassium Voltage-Gated Channel Subfamily D Member 1
Voltage-Gated Potassium Channel Subunit Kv4.1
Database Links Reactome: R-HSA-1296072
Reactome: R-HSA-5576894
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Cell Projection
Dendrite
Alternative Antibody Names Anti-Potassium Voltage-Gated Channel Subfamily D Member 1 antibody
Anti-Voltage-Gated Potassium Channel Subunit Kv4.1 antibody
Anti-KCND1 antibody

Information sourced from Uniprot.org

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