Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-KCND1 (488-647) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
KCND1 |
Gene ID: |
3750 |
Uniprot ID: |
KCND1_HUMAN |
Immunogen Region: |
488-647 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 488-647 of human KCND1 (NP_004970.3). |
Immunogen Sequence: |
TTCHEFTDELTFSEALGAVS PGGRTSRSTSVSSQPVGPGS LLSSCCPRRAKRRAIRLANS TASVSRGSMQELDMLAGLRR SHAPQSRSSLNAKPHDSLDL NCDSRDFVAAIISIPTPPAN TPDESQPSSPGGGGRAGSTL RNSSLGTPCLFPETVKISSL |
Tissue Specificity | Widely expressed. Highly expressed in brain, in particular in cerebellum and thalamus.detected at lower levels in the other parts of the brain. |
Function | Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits. |
Protein Name | Potassium Voltage-Gated Channel Subfamily D Member 1Voltage-Gated Potassium Channel Subunit Kv4.1 |
Database Links | Reactome: R-HSA-1296072Reactome: R-HSA-5576894 |
Cellular Localisation | MembraneMulti-Pass Membrane ProteinCell ProjectionDendrite |
Alternative Antibody Names | Anti-Potassium Voltage-Gated Channel Subfamily D Member 1 antibodyAnti-Voltage-Gated Potassium Channel Subunit Kv4.1 antibodyAnti-KCND1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance