Anti-KCNA3 nanobody [SAA0971] (STJN000174)
SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
General Information
| Short Description | Alpaca monoclonal nanobody anti-Potassium Voltage-Gated Channel Subfamily A Member 3 is suitable for use in ELISA research applications. |
| Applications | ELISA |
| Host | Alpaca |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA0971 |
| Isotype | VHH-8His-Cys-tag |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by Nickel column. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Target Information
| Gene Symbol | KCNA3 |
| Gene ID | 3738 |
| Uniprot ID | KCNA3_HUMAN |
Additional Info
| Function | Isoform 1: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Isoform 2: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Isoform 3: Lacks voltage-gated potassium channel activity. |
| Protein Name | Potassium Voltage-Gated Channel Subfamily A Member 3Hgk5Hlk3Hpcn3Voltage-Gated K(+ Channel HukiiiVoltage-Gated Potassium Channel Subunit Kv1.3 |
| Database Links | Reactome: R-HSA-1296072 |
| Cellular Localisation | Isoform 1: Cell MembraneMulti-Pass Membrane ProteinIsoform 2: Cell MembraneIsoform 3: CytoplasmPerinuclear Region |
| Alternative Nanobody Names | Anti-Potassium Voltage-Gated Channel Subfamily A Member 3 nanobodyAnti-Hgk5 nanobodyAnti-Hlk3 nanobodyAnti-Hpcn3 nanobodyAnti-Voltage-Gated K(+ Channel Hukiii nanobodyAnti-Voltage-Gated Potassium Channel Subunit Kv1.3 nanobodyAnti-KCNA3 nanobodyAnti-HGK5 nanobody |
Information sourced from Uniprot.org