Anti-KALRN antibody (810-890 aa) (STJ92786)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from Duo at the amino acid range 810-890
General Information
| Short Description | Rabbit polyclonal anti-Kalirin (810-890 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KALRN |
| Gene ID | 8997 |
| Uniprot ID | KALRN_HUMAN |
| Immunogen | Synthesized peptide derived from Duo at the amino acid range 810-890 |
| Immunogen Region | 810-890 aa |
| Specificity | Duo Polyclonal Antibody detects endogenous levels of Duo protein. |
Additional Info
| Post Translational Modifications | Autophosphorylated. |
| Function | Promotes the exchange of GDP by GTP. Activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, through their effects on the actin cytoskeleton. Induces lamellipodia independent of its GEF activity. |
| Protein Name | KalirinHuntingtin-Associated Protein-Interacting ProteinProtein DuoSerine/Threonine-Protein Kinase With Dbl- And Pleckstrin Homology Domain |
| Database Links | Reactome: R-HSA-193648Reactome: R-HSA-3928662Reactome: R-HSA-416476Reactome: R-HSA-416482Reactome: R-HSA-5687128Reactome: R-HSA-8980692Reactome: R-HSA-9013149Reactome: R-HSA-9013408 |
| Cellular Localisation | CytoplasmCytoskeletonAssociated With The Cytoskeleton |
| Alternative Antibody Names | Anti-Kalirin antibodyAnti-Huntingtin-Associated Protein-Interacting Protein antibodyAnti-Protein Duo antibodyAnti-Serine/Threonine-Protein Kinase With Dbl- And Pleckstrin Homology Domain antibodyAnti-KALRN antibodyAnti-DUET antibodyAnti-DUO antibodyAnti-HAPIP antibodyAnti-TRAD antibody |
Information sourced from Uniprot.org