| Host: | Rabbit |
| Applications: | WB/IP |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-JunB for use in WB and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | R01-9B7 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Purification: | Affinity Purified |
| Concentration: | 0.3 mg/mL |
| Dilution Range: | WB 1:500-1:1000IP 1:20 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | JUNB |
| Gene ID: | 3726 |
| Uniprot ID: | JUNB_HUMAN |
| Immunogen: | A synthetic peptide of human JunB |
| Post Translational Modifications | Ubiquitinated by ITCH, leading to its degradation. |
| Function | Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5'-TGAGCTCA-3'. Heterodimerizes with proteins of the FOS family to form an AP-1 transcription complex, thereby enhancing its DNA binding activity to an AP-1 consensus sequence and its transcriptional activity. |
| Protein Name | Transcription Factor JunbTranscription Factor Ap-1 Subunit Junb |
| Database Links | Reactome: R-HSA-2173796Reactome: R-HSA-6785807Reactome: R-HSA-9031628Reactome: R-HSA-9725371 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Junb antibodyAnti-Transcription Factor Ap-1 Subunit Junb antibodyAnti-JUNB antibody |
Information sourced from Uniprot.org