Anti-JMJD8 antibody (1-285) (STJ112502)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal JMJD8 (1-285) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | JMJD8 |
| Gene ID | 339123 |
| Uniprot ID | JMJD8_HUMAN |
| Immunogen Region | 1-285 |
| Immunogen Sequence | MAGGWAQGSRRAARLPEGGR LMAPASRLLALWALAAVALP GSGAEGDGGWRPGGPGAVAE EERCTVERRADLTYAEFVQQ YAFVRPVILQGLTDNSRFRA LCSRDRLLASFGDRVVRLST ANTYSYHKVDLPFQEYVEQL LHPQDPTSLGNDTLYFFGDN NFTEWASLFRHYSPPPFGLL GTAPAYSFGIAGAGSGVPFH WHGPGYSEVIYGRKRWFLYP PEKTPEFHPNKTTLAWLRD |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-285 of human JMJD8 (NP_001005920.2). |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Functions as a positive regulator of TNF-induced NF-kappa-B signaling. Regulates angiogenesis and cellular metabolism through interaction with PKM. |
| Protein Name | Jmjc Domain-Containing Protein 8Jumonji Domain-Containing Protein 8 |
| Database Links | |
| Cellular Localisation | Endoplasmic Reticulum LumenCytoplasm |
| Alternative Antibody Names | Anti-Jmjc Domain-Containing Protein 8 antibodyAnti-Jumonji Domain-Containing Protein 8 antibodyAnti-JMJD8 antibodyAnti-C16orf20 antibodyAnti-PP14397 antibody |
Information sourced from Uniprot.org