Host: | Rabbit |
Applications: | WB/IHC |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Jun dimerization protein 2 (114-163 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000IHC-P 1:50-300 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | JDP2 |
Gene ID: | 122953 |
Uniprot ID: | JDP2_HUMAN |
Immunogen Region: | 114-163 aa |
Specificity: | JDP2 Polyclonal Antibody detects endogenous levels of JDP2 protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the human JDP2 at the amino acid range 114-163 |
Function | Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin. |
Protein Name | Jun Dimerization Protein 2 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Jun Dimerization Protein 2 antibodyAnti-JDP2 antibody |
Information sourced from Uniprot.org