Anti-JAM-1/CD321 antibody {ABflo® 488} (STJ11108800)

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STJ11108800
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Applications:FC
Host:Rabbit
Reactivity:Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Isotype:IgG
Conjugation:ABflo® 488
Purification:Affinity purification
Dilution Range:FC, 5 Mu l per 10^6 cells in 100 Mu l volume
Formulation:PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis) , pH 7.3.
Storage Instruction:Store at 4°C for up to 1 year from the date of receipt. Do not freeze.
Gene Symbol:F11r
Gene ID:16456
Uniprot ID:JAM1_MOUSE
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Function Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration. Involved in platelet activation.
Protein Name Junctional Adhesion Molecule A
Jam-A
Junctional Adhesion Molecule 1
Jam-1
Cd Antigen Cd321
Database Links Reactome: R-MMU-202733
Reactome: -MMU-216083
Reactome: -MMU-2173791
Reactome: -MMU-420029
Cellular Localisation Cell Junction
Tight Junction
Cell Membrane
Single-Pass Type I Membrane Protein
Localized At Tight Junctions Of Both Epithelial And Endothelial Cells
Alternative Antibody Names Anti-Junctional Adhesion Molecule A antibody
Anti-Jam-A antibody
Anti-Junctional Adhesion Molecule 1 antibody
Anti-Jam-1 antibody
Anti-Cd Antigen Cd321 antibody
Anti-F11r antibody
Anti-Jam1 antibody
Anti-Jcam antibody
Anti-Jcam1 antibody

Information sourced from Uniprot.org

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